{"id":499,"date":"2014-05-14T14:59:00","date_gmt":"2014-05-14T05:59:00","guid":{"rendered":"https:\/\/sarabio.jp\/lab\/?p=499"},"modified":"2023-09-14T15:50:26","modified_gmt":"2023-09-14T06:50:26","slug":"%e7%ac%ac8%e5%9b%9e%e4%b8%96%e7%95%8c%e6%af%9b%e9%ab%aa%e7%a0%94%e7%a9%b6%e4%bc%9a%e8%ad%b0%e3%80%80%e3%82%b5%e3%83%a9%e3%83%b4%e3%82%a3%e3%82%aa%ef%bc%ad%ef%bc%8d%ef%bc%91%e9%96%8b%e7%99%ba-3","status":"publish","type":"post","link":"https:\/\/sarabio.jp\/lab\/index.php\/achievement\/presentation\/499\/","title":{"rendered":"\u7b2c8\u56de\u4e16\u754c\u6bdb\u9aea\u7814\u7a76\u4f1a\u8b70\u3000\u30b5\u30e9\u30f4\u30a3\u30aa\uff2d\uff0d\uff11\u958b\u767a\u30c1\u30fc\u30e0\u767a\u8868 1"},"content":{"rendered":"\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"350\" height=\"495\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051419.jpg\" alt=\"\" class=\"wp-image-500\"\/><\/figure><\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2>\u6e29\u6cc9\u85fb\u985eRG92\u304c\u7cd6\u5316\u578b\u8131\u6bdb\u75c7\u3092\u6291\u5236<\/h2>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u7b2c8\u56de\u4e16\u754c\u6bdb\u9aea\u7814\u7a76\u4f1a\u8b70\uff082014\u5e745\u670814\uff5e17\u65e5 \u97d3\u56fd\u30c1\u30a7\u30b8\u30e5\u5cf6\uff09\u306b\u304a\u3044\u3066\u3001\u6e29\u6cc9\u5927\u56fd\u65e5\u672c\u304c\u4e16\u754c\u306b\u8a87\u308b\u300c\u5225\u5e9c\u6e29\u6cc9\u300d\u304b\u3089\u767a\u898b\u3057\u305fRG92\u306b\u3088\u308b\u7cd6\u5316\u578b\u8131\u6bdb\u75c7\u306e\u6291\u5236\u306b\u3064\u3044\u3066\u5b66\u8853\u767a\u8868\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5e74\u9f62\u3068\u3068\u3082\u306b\u5897\u52a0\u3059\u308b\u7d42\u672b\u7cd6\u5316\u7523\u7269 (AGE) 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"275\" height=\"183\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051420.jpg\" alt=\"\" class=\"wp-image-501\"\/><figcaption>\u300cJAPAN SPA\u300d\u3092\u4ea4\u3048\u3066\u30ec\u30af\u30c1\u30e3\u30fc\u3092\u3059\u308b\u5bae\u7530\u535a\u58eb\u3002\u6e29\u6cc9\u5927\u56fd\u65e5\u672c\u306f\u6d77\u5916\u3067\u3082\u6709\u540d\u3002<\/figcaption><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"275\" height=\"183\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051421.jpg\" alt=\"\" class=\"wp-image-502\"\/><figcaption>\u72ec\u5275\u6027\u8c4a\u304b\u3067\u4eca\u307e\u3067\u306b\u306a\u3044\u5207\u308a\u53e3\u306e\u7814\u7a76\u6210\u679c\u306b\u820c\u3092\u5dfb\u304f\u79d1\u5b66\u8005\u3082\u3002<\/figcaption><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"275\" height=\"183\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051422.jpg\" alt=\"\" class=\"wp-image-503\"\/><figcaption>\u30ec\u30af\u30c1\u30e3\u30fc\u3092\u6c42\u3081\u308b\u58f0\u304c\u5f8c\u3092\u7d76\u305f\u305a\u7279\u306b\u6ce8\u76ee\u3092\u96c6\u3081\u305f\u767a\u8868\u3068\u306a\u308b\u3002<\/figcaption><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2>\u7814\u7a76\u6210\u679c\u306e\u6982\u8981<\/h2>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3><strong>(1) AGE\u306f\u6bdb\u4e73\u982d\u7d30\u80de\u3084\u8868\u76ae\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u306e\u5897\u6b96\u306b\u306f\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044<\/strong><\/h3>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u6bdb\u4e73\u982d\u7d30\u80de\u3001\u3042\u308b\u3044\u306f\u3001\u8868\u76ae\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8(\u6bdb\u6bcd\u7d30\u80de\u306e\u30e2\u30c7\u30eb\u3068\u3057\u3066\u4f7f\u7528)\u3092AGE\u542b\u6709\u57f9\u5730\u3067\u57f9\u990a\u3057\u3066\u3082\u3001<br>\u305d\u308c\u3089\u306e\u7d30\u80de\u5897\u6b96\u6d3b\u6027\u306b\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3><strong>(2) AGE\u306f\u9593\u8449\u7cfb-\u8868\u76ae\u7cfb\u76f8\u4e92\u4f5c\u7528\u3092\u963b\u5bb3\u3059\u308b<\/strong><\/h3>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u6bdb\u4e73\u982d\u7d30\u80de(\u9593\u8449\u7cfb\u7d30\u80de)\u3092AGE\u542b\u6709\u57f9\u5730\u3067\u57f9\u990a\u3057\u3001\u305d\u306e\u57f9\u990a\u4e0a\u6e05\u3092\u7528\u3044\u3066\u8868\u76ae\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8(\u8868\u76ae\u7cfb\u7d30\u80de)\u3092\u57f9\u990a\u3059\u308b\u3068\u3001\u305d\u306e\u5897\u6b96\u6d3b\u6027\u306f\u6709\u610f\u306b\u6291\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001AGE\u306f\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u50cd\u304d\u304b\u3051\u3001\u4f55\u3089\u304b\u306e\u8131\u6bdb\u30b7\u30b0\u30ca\u30eb\u3092\u5206\u6ccc\u3057\u3001\u3053\u306e\u963b\u5bb3\u56e0\u5b50\u304c\u6bdb\u6bcd\u7d30\u80de\u306e\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"228\" height=\"200\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051423.jpg\" alt=\"\" class=\"wp-image-504\"\/><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"275\" height=\"200\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051424.jpg\" alt=\"\" class=\"wp-image-505\"\/><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"245\" height=\"200\" src=\"https:\/\/sarabio.jp\/lab\/wp-content\/uploads\/2023\/09\/wchr2014051425.jpg\" alt=\"\" class=\"wp-image-506\"\/><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3><strong>(3)AGE\u306f\u6bdb\u4e73\u982d\u7d30\u80de\u306b\u304a\u3051\u308b\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u308b<\/strong><\/h3>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u4e0a\u8a18\u306e\u8131\u6bdb\u30b7\u30b0\u30ca\u30eb\u56e0\u5b50\u306e\u6b63\u4f53\u3092\u89e3\u660e\u3059\u308b\u305f\u3081\u306b\u3001AGE\u3092\u4f5c\u7528\u3055\u305b\u305f\u6bdb\u4e73\u982d\u7d30\u80de\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001AGE\u306f\u8131\u6bdb\u56e0\u5b50\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u308b\u4e00\u9023\u306e\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3(IL-1\u03b1\u3001IL-1\u03b2\u3001IL-6\u3001IL-8\u3001TNF-\u03b1)\u306e\u767a\u73fe\u3092\u9855\u8457\u306b\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3><strong>(4)AGE\u306fNF-\u03baB\u3092\u4ecb\u3057\u3066\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u767a\u73fe\u3092\u5897\u5f37\u3059\u308b<\/strong><\/h3>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u767a\u73fe\u306fNF-\u03baB\u7d4c\u8def\u3092\u4ecb\u3057\u3066\u4ea2\u9032\u3055\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001NF-\u03baB\u963b\u5bb3\u5264\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001AGE\u306b\u3088\u308b\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3(IL-1\u03b1\u3001IL-1\u03b2\u3001IL-6\u3001IL-8\u3001TNF-\u03b1)\u306e\u767a\u73fe\u304c\u6291\u5236\u3055\u308c\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u306f\u3001AGE\u3067\u60f9\u8d77\u3055\u308c\u305f\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u767a\u73fe\u306fNF-\u03baB\u7d4c\u8def\u3092\u4ecb\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" 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